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Tilt the vial at a slight angle while injecting the water

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The flexibility in timing allows patients to integrate the injection into their existing routines, whether that involves morning medication administration, evening self-care rituals, or alignment with weekly activities like grocery shopping or religious services

Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]

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