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121 However, CV risk reduction was not confirmed in a large prospective study of patients with T2D who were already receiving statin therapy, and there was suggestion of increased risk of stroke

Modulating a complex system carries the possibility of unintended effects that require careful study

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However, studies with existing GLP-1RAs have shown discontinuation rates of up to 30% within 1 month, and up to 6070% within 12 months of initiation [14]

An excessive amount can result in nausea, vomiting, diarrhea, heartburn, stomach cramps, and bloating, she says