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57 When combined with the non-steroidal anti-inflammatory drug (NSAID) meloxicam (Vivlodex), a micronized curcumin/palmitoyl-glucosamine complex that provided 266798 mg palmitoyl-glucosamine plus 133399 mg curcumin per day, depending on body weight, allowed for the reduction of meloxicam dose (by up to 25%) while maintaining the same degree of pain mitigation based on veterinarian evaluations

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Statistical analyses Data were analysed using R (v.4.3.2) for sequencing data and Prism (v.9.0) for statistical significance of all other data

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Introduction The physiological redox system and its implications in maintaining metabolic homeostasis in health and degenerative diseases is gaining progressive attention

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20,104,105,106,107,108 GHR dysfunction clearly protects individuals with Laron Syndrome against aging-related diseases such as cancer and diabetes, but it is unclear whether GH/IGF1 deficiency increases human lifespan, although a handful of studies have indicated that attenuated GH/IGF1 function is associated with human longevity

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