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Arsenite-induced phosphorylation of histone H3 at serine 10 is mediated by Akt1, extracellular signal-regulated kinase 2, and p90 ribosomal S6 kinase 2 but not mitogen- and stress-activated protein kinase 1
The differential diagnosis for the most common presenting symptoms of IBDs (eg, abdominal pain) is broad, and it highlights the importance of a careful examination and diagnostic workup, with diagnosis ultimately based on a combination of clinical symptoms, and results of serologic testing, imaging studies, endoscopy, and histopathology
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