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Extinction learning, a crucial step in breaking conditioned smoking behaviors, may be aided by this neurochemical effect
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It is claimed that the leaves are smoked for ritual purposes by the Navajo Indians however, smoking and/or ingesting the plant has lead to death as all parts of the plant contain chemicals that have insecticidal properties which make all parts of the plant extremely poisonous and thus unpalatable to insects and other animals.
Meltzer EO, Farrar JR, Sennett C
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