In the saxagliptin add-on to metformin HCl immediate-release trial, the incidence of diarrhea was 9.9%, 5.8%, and 11.2% in the saxagliptin 2.5 mg, 5 mg, and placebo groups, respectively
Weakness typically results from reduced caloric intake, gastrointestinal side effects, and dehydration rather than direct neuromuscular effects of the medication
Pinealon increases cell viability by suppressing free radical levels and activating proliferative processes
The example of GSH microspecies B and G (Table 2) shows that even minor changes in the sites of protonation can lead to differences in redox characteristics, this is all the more important in light of the complex, parallel protonation equilibria of these multibasic biomolecules: not only the protonation of the thiolate itself, its protonation fraction, and the concomitant redox behavior will be very sensitive to minor pH changes, but the protonation status of the adjacent basic moieties can influence the redox behavior by various inductive effects on the thiolate moiety
IFN- produced by these CD4 + and CD8 + T cells also induces hepatic synthesis of C1 esterase inhibitors (C1INH)
