As a single-center retrospective analysis, it may be subject to selection bias, and conclusions should be validated in large-scale multicenter prospective studies
doi: 10.3389/fcimb.2022.861703 101 NaendrupJHGarcia BorregaJEichenauerDAShimabukuro-VornhagenAKochanekMBllB
PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 78 H 123 N 23 O 23 S 2 Weight: 1815.12 g/mol CAS: 221231-10-3 Origin: hGH 177-191 + N-terminal tyrosine Structure: Modified peptide with disulfide bridge PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Readily soluble in water Stability: Excellent with disulfide bridge Storage: Keep refrigerated 3646 F (28 C)
Resting testosterone concentrations were elevated in C [creatine group] , however, no other significant endocrine changes were noted
Protein determinations Cells or tissues were lysed in 0.1 M NaOH and used for the determination of protein concentrations, either by the method of Lowry et al ., as described 36 or by the BCA protein assay kit (Pierce), following the manufacturer's instructions