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Serum thyroglobulin positively correlates with the volume of the thyroid gland and has been implicated in development of goiter in even nonsmoking population.[] In support of this theory clinical studies[] do report significantly higher levels of serum thyroglobulin in smokers as compared to nonsmokers and exsmokers

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In addition, tobacco smoking can cause or exacerbate other diseases such as heart disease, lung disease, and diabetes

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