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however, there was a reduction in smoking prevalence from 78.3 to 58.4 percent due to vaping, while 30 percent had quit tobacco entirely

However, the authors also found that sustained electronic cigarette use predicted an increase in self-reported depression symptoms at 12 months, thereby revealing a bidirectional relationship between depressive symptoms and electronic cigarettes (18)

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In addition, nicotine more quickly gets into the brain via the carotid artery following pulmonary absorption compared to buccal absorption, in which it travels through the liver before getting to the brain