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Intramuscular (IM) vitamin injections are administered directly into the muscle

On one hand, the clinical benefits are undeniable improved metabolic health, reduced cardiovascular risk, fewer hospitalizations, and lower long-term societal costs

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Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial

Similar to other neurotrophins, BDNF is first synthesized as a precursor protein, named pro-BDNF of 32 KDa, which is cleaved by different proteases to produce either the mature form of 14 KDa, or the truncated form of 28 KDa