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This review focuses on these advances in knowledge, including their implications for more personalised and effective management of diabetes

Patient-Level Risk Factors and Weight-Loss Magnitude Not all patients share equal vulnerability

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MBS may exert weightindependent metabolic effectssuch as enhanced insulin sensitivity and reduced systemic inflammationthat contribute to reduced surgical risk [30, 36]

Therefore, glycocalyx damage not only manifests as local pathologic changes in the organ but is also likely to be one of the common pathologic mechanisms for the progression of SAP to MODS