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GERD is associated with an increase frequency of COPD exacerbations [81]

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In 27 markets, PMI's smoke-free products contributed more than 50% of full-year net revenue, and 8 markets crossed the 75% threshold, indicating that premium device-led formats have moved beyond early adoption in several countries

The surgeon general is also suggesting a rethinking of these guidelines to include updated limits on daily alcohol consumption and greater educational efforts around the link between alcohol and cancer