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Over the course of a decade these practices could have cost countries around the world $700 million in lost tax revenues

But the budtenders at The Astor Club are even more cautious

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Consideration should be given to changing the therapeutic regimen, including possibly discontinuing the medication, in patients whose depression is persistently worse, or who are experiencing emergent suicidality or symptoms that might be precursors to worsening depression or suicidality, especially if these symptoms are severe, abrupt in onset, or were not part of the patients presenting symptoms

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