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Induction of heat shock proteins by hyperthermia and noise overstimulation in hsf1 -/- mice

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It removes the question of whether enough of the peptide successfully navigated the circulatory system to reach its destination

During development, multiple CFs innervate one immature PC, but gradually the CF-PF synapse is eliminated, and one CF forms a synapse with one PC (mono-innervation) by approximately postnatal day 20 in mice [25, 46,47,48]