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In the same study, LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry) was used to quantify the PPP intermediates (i.e., 6PGL, R5P, and S7P) produced by the wild-type and the deletion strains exposed to H 2 O 2

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Some patients benefit from biomarker assessment (fasting glucose, lipid panel, metabolic markers) before and during treatment to objectively evaluate whether therapy is meeting expected clinical milestones

Smoking and alcohol These can deplete glutathione levels , reducing effectiveness

Because the analysis combined results from multiple trials rather than individual patient data, it cannot fully capture how outcomes vary between individuals