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Readers are kindly referred to the Table 4 for the summary of current interventions to reduce the levels of TMAO

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It seems that the efficacy of B9 supplementation is dose-dependent such that, the combination of 1 mg/d folic acid, 25 mg/d vitamin B6, and 400 g/d B12 during 6 months did not have any significant effect on serum homocysteine and symptoms of migraine (74)

Much more research still needs to be carried out to determine how best to use this peptide safely and effectively [12]

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