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All participants provided written informed consent before enrollment [1]

The primary theoretical safety concern is sustained activation of the HGF/c-Met proto-oncogenic pathway, which could theoretically promote tumor initiation or growth

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Some combinations may be appropriate, but single-nutrient supplements allow for more precise dosing

Indeed, on one hand, CD36 promotes ferroptosis in key anti-tumor immunity cells, CD8 + T lymphocytes, by increasing their uptake of polyunsaturated fatty acids (PUFAs), thereby altering their cytokine production and anti-tumor activity, thus promoting tumor progression [31]