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doi: 10.1080/15563650701665076 [PubMed] 18072153 Thundiyil JG, Kearney TE, Olson KR

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p53-pS15 is a major focal point in p53 activation to mediate p53-dependent transcription or growth arrest, Ser 15 phosphorylation triggers a sequence of additional sites phosphorylation in p53 (including Ser9, -20, -46 and Thr18) that contribute further to p53 activation 28