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Dual HER2 targeting with trastuzumab and liposomal-encapsulated doxorubicin (MM-302) demonstrates synergistic antitumor activity in breast and gastric cancer

However, this approach faces limitations beyond drug efficacy, including short precorneal residence time and reduced drug absorption due to rapid lacrimal fluid turnover, extensive nasolacrimal drainage, and frequent blinking

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However, androgens can also directly stimulate the skeletal growth in patients affected by GH deficiency [34]

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