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Abbreviations ISRCTN: International Standard Randomised Controlled Trial Number RCT: Randomised controlled trial SD: Standard deviation References WHO Report on the Global Tobacco Epidemic: Offer help to quit tobacco use

Besides the alterations caused on the differentiated tissues, Tamashiro et al.28 showed that the cigarette smoke has a negative impact on the ciliogenesis process in a dose-dependent fashion to the respiratory epithelium in the maturation and differentiation phases

For those who cant quit smoking immediately, various treatments for smokers lips are available

Chen L, Li X, Chen M, Feng Y & Xiong C (2020) The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARSCoV2