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Commenters discussed the statutory requirement at section 1886(d)(4)(C)(i) of the Act to update the relative weights at least annually to reflect changes in treatment patterns, technology

doi: 10.1016/j.cmet.2021.01.015 42

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Bioavailability: By utilizing the nasal route, COBANERVE-B12 maximizes the bioavailability of Vitamin B12, ensuring optimal uptake and utilization by the body