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Nicotine increases the heart rate and blood pressure, which means that the heart isnt getting enough oxygen

The idea of gradually reducing the addictive ingredient of cigarettes, nicotine, looks attractive on the surface, said Robert West, professor of health psychology at University College London

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We found that adverse effects of cigarette smoke on surfactant were induced by tar, which is the product of burning, and other major components of cigarette smoke (nicotine, acetaldehyde, and isoprene) did not cause surfactant disruption