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Excess incidence of oral cancer is found even in communities that use traditional pn without tobacco

In moderation, nicotine is indeed used as medication not resulting in any form of addiction

Review coming soon

Early Smoking-Associated Molecular Changes in Lung Cancer Development Premalignant lung lesions and NSCLCs in smokers share mutual molecular alterations that have been reviewed elsewhere ( MYC activation in the development and progression of squamous premalignant lesions following smoking ( The concept of field cancerization was first observed and developed by Slaughter, describing sites of neoplasia and histologically adjacent normal-appearing tissue ( Smoking Rates and Spectra in LMICs: Case of Lebanon While non-communicable diseases, particularly cancer, pose a significant public health burden in high-income or upper middle-income countries, the effect is even more pronounced in low-income nations or LMICs

A smarter bet is to try more proven anti-aging strategies like walking for exercise, eating polyphenol-rich foods and supplementing with omega-3 fatty acids