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the relevance to humans remains uncertain and this is not a formal contraindication under current UK/EU labelling

PMID: 39696822 PMCID: PMC11782050 Hoteit, Kotaich, Ftouni et al

Because fats naturally slow gastric emptying even in individuals not taking semaglutide, the combined effect with the medication can lead to prolonged feelings of uncomfortable fullness, nausea, and sometimes vomiting

While refrigeration slows down degradation processes, it does not completely halt them

Eating the right diet while taking GLP-1 medications is especially important for older adults, who are already at higher risk for bone and muscle loss, Sowa says