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Oxidative stress arises when there is an imbalance between the generation of reactive oxygen species (ROS), mainly during mitochondrial oxidative phosphorylation and various enzymatic processes, and the body's ability to detoxify them through its antioxidant system (91)

Similarly, in SH-SY5Y cells, berberine resists rotenone-induced neurotoxicity through antioxidant effects and activates the PI3K/AKT signaling pathway (Deng et al., 2020)

Clinicians should ask patients if they have experienced episodes of overeating with a loss of control over eating within the past 4 weeks

View Abstract [11] Milatovic D and Aschner M

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