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Youth also attributed their e-cigarette use to a friend or family member who used them (39 percent) and the belief that e-cigarettes are less harmful than other forms of tobacco, such as cigarettes (17.1 percent)

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Indicating a structuralfunctional relation, we observed that smoking-related gray matter decreases overlapped with the acute functional effects of nicotinic agonist administration in the left insula, ventromedial PFC, and mediodorsal thalamus