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UA treatment provides antioxidant protection to dopaminergic cells by reducing Nrf2 ubiquitination and degradation and promoting its nuclear translocation, leading to transcription and expression of Nrf2-targeted antioxidant genes [175](Fig

Ingram DK, Roth GS (2021) Glycolytic inhibition: an effective strategy for developing calorie restriction mimetics

Abstract Glutamine (Gln) metabolism serves dual metabolic roles: it fuels the tricarboxylic acid (TCA) cycle, while concurrently sustaining redox balance through glutathione (GSH) synthesis

however not all of them (or actually only a few of them) can cross CNS defences with ease

Although this is promising research, no studies have been conducted on people, so more research is necessary