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ABILIFY MAINTENA (aripiprazole) is indicated: For patients who have never taken aripiprazole, establish tolerability with oral aripiprazole prior to initiating treatment with ABILIFY MAINTENA

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Acute use of lithium increases synaptic concentrations of glutamate by inhibiting neurotransmitter uptake, and chronic use leads to an increase and stabilization in the capacity of the glutamate uptake transporter in the cerebral cortex of mice with BD [34]

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