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Pathway and enrichment analysis For the biological interpretation of the differentially regulated genes, canonical pathway and upstream regulator analyses were performed using the QIAGENs Ingenuity Pathway Analysis software (IPA, QIAGEN Redwood City, www.qiagen.com/ingenuity, content version 70750971, Release Date 2021-10-22)

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[304] Outside Europe, the illicit market for amphetamine is much smaller than the market for methamphetamine and MDMA