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at the same time, oridonin increased the pro-apoptotic function of p53 by suppressing the expression of anti-apoptotic genes Bcl-2 and up-regulating the expression of genes linked to pro-apoptosis, such as p53, p-p53, p21, and Bax (165)

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3.1 Other neoplasms SSTR is highly expressed in malignant tumors but rarely in GLP-1R

6.1.5 Caffeic acid phenethyl ester The anti-inflammatory, anti-cancer, and antioxidant effects of caffeic acid phenethyl ester (CAPE) have been studied extensively (98, 99, 178181)