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His design, seemingly ahead of its time, called for the replacement of tobacco with heated flavored air (sound familiar?)

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Hence, the committee considered the body of evidence and whether results were consistent across studies following youth from different regions (e.g., Europe versus North America), youth of different age ranges (e.g., early adolescence versus late adolescence versus emerging adulthood), and those applying different methods (e.g., eliminating baseline smokers versus statistical controls)