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People who are pregnant, have active cancer, or live with certain autoimmune or endocrine conditions may not be candidates

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Given asthmas immunological complexity and heterogeneous inflammatory endotypes, further mechanistic and long-term studies including randomized clinical trials are warranted to clarify the role of GLP-1RAs in asthma management

Mutations in specific genes associated with ALS interact with key regulators of mitochondrial biogenesis, mitophagy, and mitochondrial dynamics in a direct or indirect manner, affecting the activity or number of motor neurons and the susceptibility of neuromuscular junctions