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To compare the effects of GLP-1 and placebo on maximum tolerated volume (MTV, the volume ingested until maximum satiety is reached), the same participants were given a liquid meal and used a visual analog scale to score the presence of symptoms such as bloating, fullness, nausea or pain

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In empagliflozin-treated mice, renal growth was significantly attenuated, and molecular markers of renal growth were reduced in proportion to the reduction in hyperglycemia

Together, these findings indicated the role of TGF/SMAD signalling in the induction of pancreatic fibrosis