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They deliver nicotine via an inhaled aerosol, closely mimicking the smoking experience without combustion

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For heavy smokers who previously consumed over a pack of cigarettes a day, starting with a nicotine strength of 18 to 20 mg/ml is often recommended to tackle nicotine cravings and withdrawal symptoms, as this can provide a similar level of nicotine to what they were accustomed to

1 NCI's Smoking 2007, p.7 "Guide to quitting smoking"