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The half-lives of unbound IGF-1, IGF-1 in a binary complex, and IGF-1 in a ternary complex are less than 10 minutes, 25 minutes, and more than 16 hours respectively meaning that IGF-1 activity is tightly regulated by its binding proteins

According to NIH, at least 15% of people are deficient in this powerhouse vitamin

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Some healthcare professionals may recommend the combination because of theoretical considerations