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When the inflammatory burden is high from insulin resistance, dyslipidemia (high LDL/triglycerides), high blood pressure, and liver stress it drives cholesterol particles into the artery lining and triggers the plaque buildup that can eventually rupture and cut off blood flow to the heart
Conversely, acute hypoglycaemia accelerates gastric emptying, also in a dose-dependent fashion, and almost certainly represents an important GI counter-regulatory response to hypoglycaemia
We know that these drugs not only lead to weight loss, but also provide some protection against diabetes, heart, kidney and liver disease
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