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For example, in an analysis using primary human umbilical vein endothelial cells (HUVEC) exposed to 11 commercially-available vapours, 5 were found to be acutely cytotoxic, and only 3 of those contained nicotine [24]

This is because delivering tobacco and vape products comes with many challenges, like verifying the age of the customer and managing the different regulations on these products in different states

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