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Drawing upon the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted three systematic reviews to capture all available peer-reviewed literature pertaining to chewing tobacco and five types of head and neck cancers, ischemic heart disease, and stroke

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Key considerations include labor practices, diversity and inclusion initiatives, employee engagement and retention, as well as the companys stance on human rights

Nitrosamines are still formed from these tobaccos upon combustion, but the noncombusted product contains very little or no TSNAs