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More than 66 million people 65 and older in the U.S

Table 2 Genomic DATA 1.5 Polygenic risk scores (PRS) As discussed in previous sections, exome sequencing provides a deeper understanding of the genetic basis of complex disorders, since it enables a global analysis not only of pathogenic variants but also of risk variants, variants of uncertain significance (VUS), and benign variants

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Donato A.J., Eskurza I., Silver A.E., Levy A.S., Pierce G.L., Gates P.E., Seals D.R

Following activation by redox signaling downstream of the MAPK signal pathway, the EpRE binding protein, also an oxidative stress-associated transcription factor, induces the dissociation of Nrf2 from Keap1 via redox modification and/or phosphorylation of Nrf2

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