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Treatment with PTER reduces glutamate-induced OS injury by reducing ROS and increasing the function of SOD and GSH by activating the Nrf2 signaling pathway in neuronal cells (Wang et al., 2016), a target factor for the prevention of diseases related to aging such as neurodegenerative diseases (Bhakkiyalakshmi et al., 2016
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30:57: A recent, retrospective paper on exceptionally long-lived humans finds they have low levels of IGF-1
This reversal continues to raise uncertainty and questions for plan sponsors navigating access, cost and value
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