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The most commonly reported adverse events are gastrointestinal (nausea, vomiting, diarrhea), typically mild to moderate and most frequent during dose escalation
Hence, besides biochemical evidence for the reduction of the intramolecular disulfide formed in the C-terminal domain of APR by GSH, additional evidence for other redox regulatory mechanisms remain scarce
Preservatives do not remove contamination introduced by poor handling
2B-C) and the reactive oxygen species (ROS) levels were detected via ROS staining (Fig
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