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Alternative biomarkers might also include imaging, physiology and clinical data that reflect an underlying pathophysiological process that could be responsive to therapy
The construct design supports expression of the GSH1 ORF under control of the TEF1 promoter, while a counter-selectable marker is expressed under control of the GSH-regulated pGSH1
Benkerroum N (2020) Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action
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4 Classical and non-classical effects of HO-1 4.1 An overview of HO-1 Heme oxygenase (HO) is recognized as a key enzyme in heme metabolism and plays a vital role in enabling the body to cope with stress and injury
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