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Semaglutide injections are prescribed as part of a comprehensive weight management plan that includes lifestyle changes like a balanced diet, regular physical activity, and behavior modification, says gastroenterologist and family physician Steven Batash, M.D

As long as the patient continues to maintain their results with a healthy lifestyle, even after injections have ceased, results can last forever, though that is not guaranteed

Direct answer: Yes, hunger usually increases as the medication effect fades

Semaglutide reduces stomach acid production as a secondary effect of delayed gastric emptying

(Lond.) 13 , 92 (2016)