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Dabigatran suppresses PAR-1/SphK/S1P activation of astrocytes in experimental autoimmune encephalomyelitis model

thus, the phenotype is manifest fully in males whereas female heterozygotes display varying degrees of G6PD deficiency, due to alternate X-chromosome inactivation 3,4

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10.1186/s12876-022-02264-3 109 MarinelliL

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