The results of the primary analysis for both change from baseline in HbA1c and body weight were supported by the results of the sensitivity analyses, which accounted for different sets of populations, estimands and analytical approaches to minimize bias
When your appetite drops dramatically, protein is usually the first macronutrient to suffer
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These mechanisms may support reduced food intake and weight management when treatment is combined with appropriate nutrition, physical activity and medical follow-up
Common scenarios include achieving target weight loss goals, experiencing intolerable adverse effects such as persistent nausea or gastrointestinal disturbances, financial constraints related to medication costs, pregnancy planning or confirmation (tirzepatide should be discontinued when pregnancy is recognized), or development of contraindications
