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Quick notelean mass, muscle, function, etc are a concern with all routes to weight loss not just GLP-1 Lean mass is not the same as skeletal muscle When a DXA scan, bioelectrical impedance scale, or clinical trial reports lean mass, it is not measuring skeletal muscle alone

Any medication that can cause weight gain could theoretically impact the amount of weight lost from Ozempic, Bookwalter says

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Weight management in this population should be approached with lifestyle changes and under the guidance of healthcare providers experienced in pediatric obesity management

The concern is that improved ovulation in previously anovulatory women increases fertility, and rapid weight loss may affect oral contraceptive absorption if you're having GI side effects