Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action 5-Amino-1MQ works by blocking the NNMT enzyme , which is responsible for consuming nicotinamide and depleting NAD+ stores
Additional preclinical work published in Cell Chemical Biology evaluated NNMT inhibition in similar diet-induced obesity models and confirmed the pattern: significant reductions in body weight gain, adipose tissue expansion, and circulating triglycerides compared to untreated controls
A reader who believes evidence is being hidden looks for the smoking gun
into the effect of BPC 157 on burn-wound healing and burn-gastric lesions in mice, researchers administered BPC-157 10g or 10 ng/kg via injections or topically, at the burn, as a thin layer of cream (50g of BPC 157 dissolved in 2ml of distilled water)
The process is identical to other peptides, with the dose-escalation schedule making dilution choice particularly important