4 p.m
special warnings Take special care with NICOTINELL FRUIT 2 mg SUGAR-FREE, medicated chewing gum: Consult your doctor or pharmacist if you: cardiovascular disease, eg myocardial infarction, heart failure, angina pectoris, Prinzmetal angina, heart rhythm disorder, history of stroke, high blood pressure, circulatory problems, hepatic or renal insufficiency, thyroid disease (hyperthyroidism), diabetes (follow your blood glucose more often at the beginning of the treatment as it can be altered), pheochromocytoma ( disease of the adrenal glands causing severe hypertension ), inflammation of the mouth or throat, esophagitis, gastritis, ulcer of the stomach or duodenum
For shipments outside EU of authentic Swedish snus products feel free to visit our worldwide shop www.theroyalsnus.com
[416] Compared to naloxone which has a half-life of approximately 2 hours and also rapidly reverses the effects of an opioid overdose, nalmefene has a half-life of 11 hours which means that it remains in the body much longer than other overdose reversal drugs
Nicotine pouch manufacturers recommend using one pouch for approximately 30 min [61]