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These differences in GST type and multiplicity, as well as residue changes that impact the secondary and tertiary structure of the cat and dog GST proteins, affect substrate selectivity and catalytic efficiency

It also plays crucial roles in the immune response, DNA repair, mitochondrial function and the detoxification of drugs, chemicals, heavy metals, radiation, metabolic wastes, and other toxins and carcinogens

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Cartilage and joint repair models: Intraarticular injection of AOD9604 in a collagenase induced rabbit osteoarthritis model showed improved cartilage architecture and regeneration