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Applied In Vitro Toxicology, 3 (1), 2840

They concluded ECV can elevate level of damaged mitochondrial DNA in circulating blood and induce the expression of toll-like receptor 9 (TLR9), thereby increasing the expression of proinflammatory cytokines in monocyte/macrophage, which is responsible for atherosclerosis

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Plain tobacco packaging, increased graphic health warnings and adolescents' perceptions and initiation of smoking: DePICT, a French nationwide study BMJ Tobbaco Control, November 2018